I know there are a lot of programs that deal with all sorts of malware from cookies to hacking tools (ohnoes). But in this thread I'd like to confine discussion to the elmination of virus and trojan programs primarily.
Essentially my quandry is that I've heard a million and one good things about nod32 and Avast! but when it comes to my personal experience, they seem to come up really short.
I've had Avast! installed on my computer for a long time now, and it's never detected a virus or other malware (except for a false positive caused by Panda's lack of encryption on their database file from activescan). But when I bother to scan with trendmicro's housecall or panda's activescan I get inexplicable trojans detected, it's happened twice now, and reading the supposed trojan's location doesn't help (one of them was a pseudo false positive on tooleaky.exe which was a program designed to demonstrate the necessity of application hijacking detection in outbound firewall filters).
Most recently, I think it was panda that found one "Spyware_KEYL_astlog", in a folder that went by the name of nirsoft. After googling I found that nirsoft could I guess proc a false positive with the type of software they develop, but I don't ever remember installing or downloading anything from nirsoft.
Anyway that's the gist of where I'm at right now. I wouldn't call this a question per se, so if no one has anything to add or doesn't care, don't worry about it. I just thought it might be something worth discussing as I didn't find anything this concrete using Google.