Hard drives are hard drives (at least current types). There are currently two types of 3.5" units out there - SATA and PATA (formally EIDE). I would assume the HD in the case is SATA, since that is the current standard. If you wished to install it into the computer directly, your motherboard will need to have an SATA jack. To have one, your computer/motherboard will need to have been made within the last 3 or 4 years. If you have an older computer that does not have an SATA jack, you can still install it internally by adding an SATA PCI card like this one -
http://www.tigerdirect.com/applicati...348&CatId=1455 - otherwise, if you wish to keep it external, using a replacement HD Case like this one -
http://www.tigerdirect.com/applicati...7&Sku=T13-5026 - will do.
An SATA cable will be needed to install this drive into your computer as well, such as this -
http://www.tigerdirect.com/applicati...73414&CatId=84
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