The problem with the 64-bit version of DNS is not that it won't work in a 64-bit environment. If you could get it installed, it would work in a 64-bit environment. In fact, some of us have done this by going through the back door. However, the problem with running DNS 9.5 in a 64-bit environment is that it works fine for 32-bit applications, but the 64-bit thunking requires an excessive amount of time and results in DNS performing way too slowly. The reason that Nuance has locked out the ability to install it on a 64-bit OS is because they don't want the technical support nightmare that would result. In other words, if they were to allow it to be installed on a 64-bit OS they would end up getting 10 times the number of complaints from users who would say, "If I can install it on a 64-bit OS, why does it support fully 64-bit applications?" And, in addition, they would receive nothing but complaints saying that if you're going to make it installable on a 64-bit OS, why isn't it fully compatible with 64-bit applications. In other words, they're damned if they do and damned if they don't. Therefore, it's a lot less expensive and a lot easier to deal with the "damned if they don't" side of the coin.
This question is obviously dated but if anyone else out there was curious this is the answer. | 
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Windows Vista 
