Ok, it looks like I had the same error as a lot of other people. And reading this I think I have found the answer (at least it worked for me!!!!

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I had installed a Card Reader into a USB port to download from my digital camera. I have Quicktime and do not use Nortons!!!
The only time I got the error was when I started to open ONE CERTAIN GAME on my Desktop---it would take at least 5 cancels to get rid of it and the game would then open and that is when I came here to check for a fix. And thanks to all the poeple telling all the tricks that they used I "discovered" mine!!!
Since I have downloaded all the pictures that I have NOW and don't need the Card Reader RIGHT NOW I uninstalled the Software for my Card Reader and took it OUT of the USB port----NO MORE ERROR--
Now, I have fixed mine---not to say that this is the issue for all but to me it seems that it had something to do with the USB and the Card Reader (at least on my PC)

to everyone that I read and took me in the right direction!!!