Alright I've tried basically everything I could think of with this. I've unplugged and plugged my mouse and keyboard in every single USB port, I've tried to log into safe mode, and I've booted from a bootable USB and CD and even on new partitions they still won't work. I just upgraded my motherboard + CPU from an I5 3450 to an AMD Ryzen 5 2600. At this point I'm just desperate and don't know what to do.
Edit: The mouse and keyboard work in the BIOS, they just don't work when Windows loads up (even the numpad light goes off)
Edit: The mouse and keyboard work in the BIOS, they just don't work when Windows loads up (even the numpad light goes off)