mouse clicking sometimes won't open

This is a minor problem, but irritating. Sometimes when i click on an icon or program, it will not do anything. Is it my mouse-have wireless-,but haven't had any problems before this.

 

One thing I would recommend doing would be to try your mouse on a different computer. If it does the same thing, you may need a new mouse. At the same time, you might want to try using a known good mouse on the computer that seems to be messing up. Doing a cross-check like this might lead to some answers.

-Wes