Task Manager disabled, Cant run any apps, Help

For the past 24 hours i my computer has been experiencing issues such as no-disk error after booting, applications will not initialize, the task manager is disabled and regedit can not be accessed.

HijackThis log

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 3:57:56 PM, on 3/21/2010
Platform: Windows Vista SP1 (WinNT 6.00.1905)
MSIE: Internet Explorer v7.00 (7.00.6001.18294)
Boot mode: Normal

Running processes:
C:\Program Files (x86)\Spybot - Search & Destroy\TeaTimer.exe
C:\Program Files (x86)\IOI\ButtonMonitor.exe
L:\stinger1010843.exe
C:\Program Files (x86)\Mozilla Firefox\firefox.exe
C:\Program Files (x86)\Trend Micro\HijackThis\HijackThis.exe
C:\Windows\SysWOW64\NOTEPAD.EXE

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.gateway.com/g/startpage.html?Ch=Retail&SubCH=&Br=GTW&Loc=ENG_US&Sys=DTP&M=GT5676
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.gateway.com/g/startpage.html?Ch=Retail&SubCH=&Br=GTW&Loc=ENG_US&Sys=DTP&M=GT5676
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.gateway.com/g/startpage.html?Ch=Retail&SubCH=&Br=GTW&Loc=ENG_US&Sys=DTP&M=GT5676
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.gateway.com/g/sidepanel.html?Ch=Retail&SubCH=&Br=GTW&Loc=ENG_US&Sys=DTP&M=GT5676
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = :0
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
F2 - REG:system.ini: UserInit=userinit.exe
O1 - Hosts: ::1 localhost
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files (x86)\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~2\SPYBOT~1\SDHelper.dll
O2 - BHO: NCO 2.0 IE BHO - {602ADB0E-4AFF-4217-8AA1-95DAC4DFA408} - (no file)
O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\PROGRA~2\MICROS~2\Office12\GRA8E1~1.DLL
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files (x86)\Java\jre1.6.0_04\bin\ssv.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files (x86)\Google\GoogleToolbarNotifier\5.1.1309.3572\swg.dll
O2 - BHO: Google Gears Helper - {E0FEFE40-FBF9-42AE-BA58-794CA7E3FB53} - C:\Program Files (x86)\Google\Google Gears\Internet Explorer\0.5.33.0\gears.dll
O3 - Toolbar: (no name) - {7FEBEFE3-6B19-4349-98D2-FFB09D4B49CA} - (no file)
O3 - Toolbar: (no name) - {CCC7A320-B3CA-4199-B1A6-9F516DD69829} - (no file)
O4 - HKLM\..\Run: [StartCCC] "C:\Program Files (x86)\ATI Technologies\ATI.ACE\Core-Static\CLIStart.exe"
O4 - HKLM\..\Run: [ButtonMonitor] C:\Program Files (x86)\IOI\ButtonMonitor.exe
O4 - HKLM\..\Run: [GrooveMonitor] "C:\Program Files (x86)\Microsoft Office\Office12\GrooveMonitor.exe"
O4 - HKLM\..\RunOnce: [Launcher] %WINDIR%\SMINST\launcher.exe
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files (x86)\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Run: [ehTray.exe] C:\Windows\ehome\ehTray.exe
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE')
O7 - HKCU\Software\Microsoft\Windows\CurrentVersion\Policies\System, DisableRegedit=1
O8 - Extra context menu item: Add to Google Photos Screensa&ver - res://C:\Windows\system32\GPhotos.scr/200
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~2\MICROS~2\Office12\EXCEL.EXE/3000
O9 - Extra button: (no name) - {09C04DA7-5B76-4EBC-BBEE-B25EAC5965F5} - C:\Program Files (x86)\Google\Google Gears\Internet Explorer\0.5.33.0\gears.dll
O9 - Extra 'Tools' menuitem: &Gears Settings - {09C04DA7-5B76-4EBC-BBEE-B25EAC5965F5} - C:\Program Files (x86)\Google\Google Gears\Internet Explorer\0.5.33.0\gears.dll
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~2\MICROS~2\Office12\REFIEBAR.DLL
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~2\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~2\SPYBOT~1\SDHelper.dll
O13 - Gopher Prefix:
O16 - DPF: {0CCA191D-13A6-4E29-B746-314DEE697D83} (Facebook Photo Uploader 5 Control) - http://upload.facebook.com/controls/2008.10.10_v5.5.8/FacebookPhotoUploader5.cab
O16 - DPF: {4871A87A-BFDD-4106-8153-FFDE2BAC2967} (DLM Control) - http://dlm.tools.akamai.com/dlmanager/versions/activex/dlm-activex-2.2.4.1.cab
O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\PROGRA~2\MICROS~2\Office12\GR99D3~1.DLL
O23 - Service: @%SystemRoot%\system32\Alg.exe,-112 (ALG) - Unknown owner - C:\Windows\System32\alg.exe (file missing)
O23 - Service: ASP.NET State Service (aspnet_state) - Unknown owner - C:\Windows\Microsoft.NET\Framework\v2.0.50727\aspnet_state.exe (file missing)
O23 - Service: Ati External Event Utility - Unknown owner - C:\Windows\system32\Ati2evxx.exe (file missing)
O23 - Service: Autodesk Licensing Service - Autodesk - C:\Program Files (x86)\Common Files\Autodesk Shared\Service\AdskScSrv.exe
O23 - Service: DCPFLICS - Unknown owner - C:\Program Files (x86)\DCPFLICS\DCPFLICS.exe
O23 - Service: @dfsrres.dll,-101 (DFSR) - Unknown owner - C:\Windows\system32\DFSR.exe (file missing)
O23 - Service: dlba_device - - C:\Windows\system32\dlbacoms.exe
O23 - Service: FLEXnet Licensing Service - Acresso Software Inc. - C:\Program Files (x86)\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: @keyiso.dll,-100 (KeyIso) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @comres.dll,-2797 (MSDTC) - Unknown owner - C:\Windows\System32\msdtc.exe (file missing)
O23 - Service: NBService - Nero AG - C:\Program Files (x86)\Nero\Nero 7\Nero BackItUp\NBService.exe
O23 - Service: @%SystemRoot%\System32\netlogon.dll,-102 (Netlogon) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: NMIndexingService - Nero AG - C:\Program Files (x86)\Common Files\Ahead\Lib\NMIndexingService.exe
O23 - Service: PnkBstrA - Unknown owner - C:\Windows\system32\PnkBstrA.exe
O23 - Service: @%systemroot%\system32\psbase.dll,-300 (ProtectedStorage) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: ProtexisLicensing - Unknown owner - C:\Windows\SysWOW64\PSIService.exe
O23 - Service: @%systemroot%\system32\Locator.exe,-2 (RpcLocator) - Unknown owner - C:\Windows\system32\locator.exe (file missing)
O23 - Service: @%SystemRoot%\system32\samsrv.dll,-1 (SamSs) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: SBSD Security Center Service (SBSDWSCService) - Safer Networking Ltd. - C:\Program Files (x86)\Spybot - Search & Destroy\SDWinSec.exe
O23 - Service: @%SystemRoot%\system32\SLsvc.exe,-101 (slsvc) - Unknown owner - C:\Windows\system32\SLsvc.exe (file missing)
O23 - Service: @%SystemRoot%\system32\snmptrap.exe,-3 (SNMPTRAP) - Unknown owner - C:\Windows\System32\snmptrap.exe (file missing)
O23 - Service: @%systemroot%\system32\spoolsv.exe,-1 (Spooler) - Unknown owner - C:\Windows\System32\spoolsv.exe (file missing)
O23 - Service: TabletServiceWacom - Unknown owner - C:\Windows\system32\Wacom_Tablet.exe (file missing)
O23 - Service: @%SystemRoot%\system32\ui0detect.exe,-101 (UI0Detect) - Unknown owner - C:\Windows\system32\UI0Detect.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vds.exe,-100 (vds) - Unknown owner - C:\Windows\System32\vds.exe (file missing)
O23 - Service: @%systemroot%\system32\vssvc.exe,-102 (VSS) - Unknown owner - C:\Windows\system32\vssvc.exe (file missing)
O23 - Service: @%Systemroot%\system32\wbem\wmiapsrv.exe,-110 (wmiApSrv) - Unknown owner - C:\Windows\system32\wbem\WmiApSrv.exe (file missing)
O23 - Service: @%ProgramFiles%\Windows Media Player\wmpnetwk.exe,-101 (WMPNetworkSvc) - Unknown owner - C:\Program Files (x86)\Windows Media Player\wmpnetwk.exe (file missing)
O23 - Service: XAudioService - Unknown owner - C:\Windows\system32\DRIVERS\xaudio64.exe (file missing)

--
End of file - 9127 bytes