The Coronavirus - What's Happening Around the World

Johnny b

John
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Another variant of interest:

New COVID variant found in France: Reason for panic or not quite yet?
https://www.jpost.com/health-and-we...ance-reason-for-panic-or-not-quite-yet-684878

The spike protein of the variant known as B.1.640 has some unprecedented mutations.

................ One in particular has drawn attention: the spike protein, which is what allows the virus to cling to the human cell and start the infection process, has some deletions.
The question is whether this will make the virus more or less infectious.
...............
“This variant exemplifies that if you leave some of the world’s population without access to vaccines, then the virus will continue to multiply and it will lead to more variants,” Cohen said.
 

Johnny b

John
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More on Merck's 'game changer': molnupiravir

First, the scientist: William A. Haseltine
A reputable authority with a lifetime of achievements.
https://en.wikipedia.org/wiki/William_A._Haseltine


A prominent virologist warns COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm
https://www.science.org/content/art...ngerous-mutants-others-see-little-cause-alarm
Now, William Haseltine, a virologist formerly at Harvard University known for his work on HIV and the human genome project, suggests that by inducing viral mutations, molnupiravir could spur the rise of new viral variants more dangerous than today’s. “You are putting a drug into circulation that is a potent mutagen at a time when we are deeply concerned about new variants,” says Haseltine, who outlined his concern Monday in a Forbes blog post. “I can’t imagine doing anything more dangerous.”
..........
Underpinning Haseltine’s worry are studies that show coronaviruses can survive with molnupiravir-induced mutations.
_______________________

Forbes article by Haseltine:

Supercharging New Viral Variants: The Dangers Of Molnupiravir (Part 1)
https://www.forbes.com/sites/willia...-variants-the-dangers-of-molnupiravir-part-1/

Harming Those Who Receive It: The Dangers Of Molnupiravir (Part 2)
https://www.forbes.com/sites/willia...eceive-it-the-dangers-of-molnupiravir-part-2/


Too much to copy and paste, but this stands out in his first article:
We are potentially headed towards a world class disaster.
This in the second article:
Today, my focus is on the people who may receive the drug as a treatment and the possibility that molnupiravir could lead to cancerous tumors in those patients and birth defects in the unborn.
There is much to read and consider in both articles.
 

Johnny b

John
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First Known COVID Case Was Vendor at Wuhan Market, Scientist Claims
(repost from the NewYork Times )
https://news.yahoo.com/first-known-covid-case-vendor-131118427.html

A scientist who has pored over public accounts of early COVID-19 cases in China reported Thursday that an influential World Health Organization inquiry had likely gotten the early chronology of the pandemic wrong. The new analysis suggests that the first known patient sickened with the coronavirus was a vendor in a large Wuhan animal market, not an accountant who lived many miles from it.
 

flavallee

Frank
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I got my Pfizer booster shot today. (y)

Now we have to wait and see what the new variance will do and if a second booster shot will be necessary. :unsure:
 

Johnny b

John
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Merck says its Covid antiviral treatment less effective than first thought
https://www.ft.com/content/5991288f-7e62-4de4-9d41-88285d29ee62

Merck’s Covid-19 oral antiviral treatment is not as effective as first thought, the pharma group said on Friday, after a full analysis of trial results provided new data on its ability to reduce hospitalisations and deaths.

The company said its oral drug, molnupiravir, showed a relative risk reduction of 30 per cent when compared with placebo in all 1,400 enrolled patients on the trial. It had said last month that reduction was of “approximately” 50 per cent as it published preliminary data on a smaller sample of patients.
 

Johnny b

John
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Womp, womp: Efficacy of Merck’s Thor-inspired COVID pill crumbles, vexing experts
https://arstechnica.com/science/202...-inspired-covid-pill-crumbles-vexing-experts/

In a 13-to-10 vote, advisors for the Food and Drug Administration narrowly supported authorizing Merck's Thor-inspired antiviral pill molnupiravir for use against severe COVID-19.

Molnupiravir's final data and today's vote is a significant disappointment from the early fanfare around the drug...........

AMDAC members largely felt that Merck had not done enough safety monitoring to better understand the risk of mutations in people, particularly in pregnant people.

Following the close vote and many expressions of concern, the FDA will now decide if it will issue an emergency use authorization for molnupiravir.
 

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