Weird Windows 7 Mouse/Cursor Issue

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NuancedPotato

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Mar 11, 2015
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So I've been having a bizarre problem with Windows 7 for awhile now where at certain points during normal use the cursor will not interact with anything when I click. I can move the cursor around, but I cannot click on anything. I end up having to CTRL+ALT+DEL and start the task manager to make things normal again. I don't end any processes, merely opening the task manager fixes it (for the most part). I could almost live with that if it didn't do something much worse on certain programs. So for example, a program I use called NifSkope (A mesh file editing tool) has multiple sub windows for various things I.E. render window for the mesh, Tools, Options, ETC. If I click on one particular sub window, I cannot interact with any of the others. I don't have a consistent fix for this one, which is incredibly annoying. This problem is not exclusive to this program, but affects very few others. The minor one happens quite often at start-up, and happens seemingly randomly throughout general use on my PC, though it never occurs in video games. I'm pretty sure it's not a mouse issue (I use a Razer Deathadder 2013 Edition) I've tested it on other PCs without issue, and used two different mice on the affected PC. Mouse keys even suffer from the issue. I'm a stubborn guy who doesn't usually seek out tech help, but if anybody can provide assistance I'd be very grateful because I'm just at a loss with this one.

Tech Specs:
OS: Microsoft Windows 7 Ultimate Service Pack 1 64 bit
Processor: Intel i7-3770K Quad Core @ 3.50GHz
RAM: 32 GB (8x4)
Graphics Card: NVIDIA GeForce GTX 980
HDD/SSD: C: Samsung 840 EVO 240GB SSD D: Western Digital Black 2TB HDD
Motherboard: ASUS P8Z77-V (Latest Bios)
PSU: Corsair 750 Watt

EDIT: This doesn't only affect one partition, I've tested other versions of Windows 7 and the problem persists. Maybe a motherboard issue?
 
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